Either because the file is in use or because it has denied you access, with Unlocker you can remove it. With only one right click on the file or folder, open the context menu and select the 'unlocker' wand.
With this small gesture, you can eliminate any item. Also, you can do things like change the name of folders and move files. There are lots of secondary utilities within the program.
Unlocker is a very useful tool, that will at times save you from a lot of frustration.